NF2 Peptide
€100.00
In stock
SKU
350518
Protein Family: Receptors and Channels
Pathway and Disease: Cancers, Nervous and Sensory Systems
Alternate Names: Merlin; Moesin-ezrin-radixin-like protein; neurofibromin-2; Schwannomin; Schwannomerlin; NF2; SCH
Accession No.: P35240, NP_000259
Description:
Merlin (NF2) acts as a membrane stabilizing protein and may inhibit PI3 kinase by binding to CENTG1. Defects in NF2 are the cause of neurofibromatosis 2 and schwannnomatosis (neuromas).
Format:
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 2043.4 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200156 is selected from a sequence within the C-term region of human NF2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C86H155N29O26S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Pathway and Disease: Cancers, Nervous and Sensory Systems
Alternate Names: Merlin; Moesin-ezrin-radixin-like protein; neurofibromin-2; Schwannomin; Schwannomerlin; NF2; SCH
Accession No.: P35240, NP_000259
Description:
Merlin (NF2) acts as a membrane stabilizing protein and may inhibit PI3 kinase by binding to CENTG1. Defects in NF2 are the cause of neurofibromatosis 2 and schwannnomatosis (neuromas).
Format:
Each vial contains 0.1 mg of lyophilized peptide. Reconstitute with 0.1 ml deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 2043.4 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200156 is selected from a sequence within the C-term region of human NF2. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C86H155N29O26S1
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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