NF68 (clone NR4), anti-human, rat, pig
€354.00
In stock
SKU
ARP-10-M1070
Catalog Number: 10-M1070
Size: 100 µg
Isotype: Mouse IgG1
Size: 100 µg
Isotype: Mouse IgG1
Background:
Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 kD(NFL), 125 kD(NFM) and 200 kD(NFH) on SDS-gel electrophoresis. And they have a role in the maturation of regenerating myelinated axons. Neurofilament 68(NF68), also called Neurofilament Protein, Light Chain(NFL). It is one of the most abundant cytoskeletal components of the neuron. Mutations in this gene were reported as a cause for autosomal dominant Charcot-Marie-Tooth type 2E(CMT2E) linked to chromosome 8p21. NFL was identified repeatedly in both screenings and found to interact with Myotubularin-related 2 gene, MTMR2 in both Schwann cells and neurons.
Decription:
Mouse IgG monoclonal antibody for NF68, neurofilament, light polypeptide (NEFL ) detection. Tested with WB, IHC-P, IHC-F in Human, pig, rat. No cross reactivity with other proteins.
Synonyms: NFL, NF-L, NF68, CMT1F, CMT2E, 68 kDa neurofilament protein, Neurofilament triplet L protein
Clone: NR4
Isotype: Mouse IgG1
Immunogen: Pig spinal cord.
Reactivity: human, pig, rat
Form: Lyophilized; Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Applications: WB, IHC-P, IHC-F
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
Neurofilaments are composed of 3 neuron-specific proteins with apparent molecular masses of 68 kD(NFL), 125 kD(NFM) and 200 kD(NFH) on SDS-gel electrophoresis. And they have a role in the maturation of regenerating myelinated axons. Neurofilament 68(NF68), also called Neurofilament Protein, Light Chain(NFL). It is one of the most abundant cytoskeletal components of the neuron. Mutations in this gene were reported as a cause for autosomal dominant Charcot-Marie-Tooth type 2E(CMT2E) linked to chromosome 8p21. NFL was identified repeatedly in both screenings and found to interact with Myotubularin-related 2 gene, MTMR2 in both Schwann cells and neurons.
Decription:
Mouse IgG monoclonal antibody for NF68, neurofilament, light polypeptide (NEFL ) detection. Tested with WB, IHC-P, IHC-F in Human, pig, rat. No cross reactivity with other proteins.
Synonyms: NFL, NF-L, NF68, CMT1F, CMT2E, 68 kDa neurofilament protein, Neurofilament triplet L protein
Clone: NR4
Isotype: Mouse IgG1
Immunogen: Pig spinal cord.
Reactivity: human, pig, rat
Form: Lyophilized; Mouse ascites fluid, 1.2% sodium acetate, 2mg BSA, with 0.01mg NaN3 as preservative.
Applications: WB, IHC-P, IHC-F
Reconstitution: Add 1ml of PBS buffer will yield a concentration of 100ug/ml.
Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.
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