NFAT4 polyclonal, anti-human, mouse
€388.00
In stock
SKU
BS71918
Background:
NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurindependent 4) is a member of the nuclear factors of activated T cells DNAbinding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. This complex consists of at least two components, a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.
Alternative Name:
Nuclear factor of activated T-cells, cytoplasmic 3, NF-ATc3, NFATc3, NFATx, T-cell transcription factor NFAT4, NF-AT4, NFAT4, NFATC3
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: NFAT4 polyclonal antibody detects endogenous levels of NFAT4 protein.
Immunogen:
Recombinant protein of human NFATC3
MW: 130kDa
Swis Prot.: Q12968
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
NFATc4 (nuclear factor of activated T cells, cytoplasmic, calcineurindependent 4) is a member of the nuclear factors of activated T cells DNAbinding transcription complex that influences cytokine gene expression, cardiac hypertrophy and adipocyte differentiation. This complex consists of at least two components, a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family participate in the formation of this complex. NFATc4 plays a role in the inducible expression of cytokine genes in T cells, including the induction of IL-2 and IL-4. p38 MAP kinase phosphorylates multiple residues in the NFAT homology domain of NFATc4.
Alternative Name:
Nuclear factor of activated T-cells, cytoplasmic 3, NF-ATc3, NFATc3, NFATx, T-cell transcription factor NFAT4, NF-AT4, NFAT4, NFATC3
Application Dilution: WB: 1:500 - 1:2000, IF: 1:50 - 1:200
Specificity: NFAT4 polyclonal antibody detects endogenous levels of NFAT4 protein.
Immunogen:
Recombinant protein of human NFATC3
MW: 130kDa
Swis Prot.: Q12968
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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