NFATC1 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13900b
Background:
The product of this gene is a component of the nuclearfactor of activated T cells DNA-binding transcription complex. Thiscomplex consists of at least two components: a preexistingcytosolic component that translocates to the nucleus upon T cellreceptor (TCR) stimulation, and an inducible nuclear component.Proteins belonging to this family of transcription factors play acentral role in inducible gene transcription during immuneresponse. The product of this gene is an inducible nuclearcomponent. It functions as a major molecular target for theimmunosuppressive drugs such as cyclosporin A. Five transcriptvariants encoding distinct isoforms have been identified for thisgene. Different isoforms of this protein may regulate inducibleexpression of different cytokine genes.
Other Names:
Nuclear factor of activated T-cells, cytoplasmic 1, NF-ATc1, NFATc1, NFAT transcription complex cytosolic component, NF-ATc, NFATc, NFATC1, NFAT2, NFATC
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13900b was selected from the C-term region of NFATC1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NFATC1
Gene ID: 4772
Primary Accession: O95644
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
The product of this gene is a component of the nuclearfactor of activated T cells DNA-binding transcription complex. Thiscomplex consists of at least two components: a preexistingcytosolic component that translocates to the nucleus upon T cellreceptor (TCR) stimulation, and an inducible nuclear component.Proteins belonging to this family of transcription factors play acentral role in inducible gene transcription during immuneresponse. The product of this gene is an inducible nuclearcomponent. It functions as a major molecular target for theimmunosuppressive drugs such as cyclosporin A. Five transcriptvariants encoding distinct isoforms have been identified for thisgene. Different isoforms of this protein may regulate inducibleexpression of different cytokine genes.
Other Names:
Nuclear factor of activated T-cells, cytoplasmic 1, NF-ATc1, NFATc1, NFAT transcription complex cytosolic component, NF-ATc, NFATc, NFATC1, NFAT2, NFATC
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13900b was selected from the C-term region of NFATC1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NFATC1
Gene ID: 4772
Primary Accession: O95644
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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