NFATC1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS6677
Background:
NFATc1 is present in uninduced cells and translocates to the nucleus upon calcium mobilization. The phosphatase calcineurin promotes nuclear accumulation of NF-ATc. PKA causes phosphorylation and cytoplasmic accumulation of NF-ATc1 in direct opposition to calcineurin by phosphorylating Ser-245, Ser-269, and Ser-294 in the conserved serine-proline repeat domain.
Alternative Name:
cytoplasmic 1, MGC138448, NF ATc, NF ATc1, NF-ATc, NF-ATc1, NFAC1, NFAT 2, NFAT transcription complex cytosolic component, NFAT2, NFATC 1, NFATc, NFATc1, Nuclear factor of activated T cells cytoplasmic 1, Nuclear factor of activated T-cells,
Application Dilution: WB: 1:500 - 1:2000
Specificity: NFATC1 polyclonal antibody detects endogenous levels of NFATC1 protein.
Immunogen:
Recombinant full length Human NFATC1.
MW: ~ 78, 101kDa
Swis Prot.: O95644
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
NFATc1 is present in uninduced cells and translocates to the nucleus upon calcium mobilization. The phosphatase calcineurin promotes nuclear accumulation of NF-ATc. PKA causes phosphorylation and cytoplasmic accumulation of NF-ATc1 in direct opposition to calcineurin by phosphorylating Ser-245, Ser-269, and Ser-294 in the conserved serine-proline repeat domain.
Alternative Name:
cytoplasmic 1, MGC138448, NF ATc, NF ATc1, NF-ATc, NF-ATc1, NFAC1, NFAT 2, NFAT transcription complex cytosolic component, NFAT2, NFATC 1, NFATc, NFATc1, Nuclear factor of activated T cells cytoplasmic 1, Nuclear factor of activated T-cells,
Application Dilution: WB: 1:500 - 1:2000
Specificity: NFATC1 polyclonal antibody detects endogenous levels of NFATC1 protein.
Immunogen:
Recombinant full length Human NFATC1.
MW: ~ 78, 101kDa
Swis Prot.: O95644
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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