NFATC1 polyclonal (C-term), anti-human

NFATC1 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP13900b
Catalog Number: AC-AP13900b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB34041
Applications: IHC-P, WB
Datasheet

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Background:
The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.

Other Names:
Nuclear factor of activated T-cells, cytoplasmic 1, NF-ATc1, NFATc1, NFAT transcription complex cytosolic component, NF-ATc, NFATc, NFATC1, NFAT2, NFATC

Target/Specificity:
This NFATC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 898-927 amino acids from the C-terminal region of human NFATC1.

Antigen Region:
898-927

Antigen Type: Synthetic Peptide

Gene Name: NFATC1
Gene ID: 4772
Primary Accession: O95644
NCBI Accession: NP_001265598.1;NP_001265599.1;NP_001265601.1;NP_001265602.1;NP_001265604.1;NP_006153.2;NP_765975.1;NP_765976.1;NP_765977.1;NP_765978.1
Other Accession: NP_765977.1;NP_765978.1;NP_765975.1;NP_006153.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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