NFATC2 Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP7766b
Background:
NFATC2 is a member of the nuclear factor of activated T cells (NFAT) family. This protein is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). It is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response.
Other Names:
Nuclear factor of activated T-cells, cytoplasmic 2, NF-ATc2, NFATc2, NFAT pre-existing subunit, NF-ATp, T-cell transcription factor NFAT1, NFATC2, NFAT1, NFATP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7766b was selected from the N-term region of human NFATC2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NFATC2
Gene ID: 4773
Primary Accession: Q13469
Other Accession: NP_036472
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
NFATC2 is a member of the nuclear factor of activated T cells (NFAT) family. This protein is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). It is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response.
Other Names:
Nuclear factor of activated T-cells, cytoplasmic 2, NF-ATc2, NFATc2, NFAT pre-existing subunit, NF-ATp, T-cell transcription factor NFAT1, NFATC2, NFAT1, NFATP
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7766b was selected from the N-term region of human NFATC2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NFATC2
Gene ID: 4773
Primary Accession: Q13469
Other Accession: NP_036472
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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