NFATC2 Polyclonal Antibody

Background:
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Immunology, Signal Transduction

Synonyms:
AI607462, cytoplasmic 2, KIAA0611, NF ATc2, NF ATp, NF-ATc2, NF-ATp, NFAC2, NFAT 1, NFAT pre existing subunit, NFAT pre-existing subunit, NFAT transcription complex, preexisting component, NFAT1, NFAT1-D, NFATc2, NFATp, Nuclear factor of activated T cells cytoplasmic 2, Nuclear factor of activated T cells cytoplasmic calcineurin dependent 2, Nuclear factor of activated T cells pre-existing component, Nuclear factor of activated T cells, preexisting component, Nuclear factor of activated T-cells, Preexisting nuclear factor of activated T cells 2, T cell transcription factor NFAT 1, T-cell transcription factor NFAT1

Immunogen: Synthetic peptide of human NFATC2

Swissprot: Q13469
Gene Accession: NP_001129493

Calculated MW: 98 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.7 mg/mL
Dilution: WB 1:200-1:1000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-23815/sc-13034