NFATC2 Polyclonal Antibody

Background:
This gene is a member of the nuclear factor of activated T cells (NFAT) family. The product of this gene is a DNA-binding protein with a REL-homology region (RHR) and an NFAT-homology region (NHR). This protein is present in the cytosol and only translocates to the nucleus upon T cell receptor (TCR) stimulation, where it becomes a member of the nuclear factors of activated T cells transcription complex. This complex plays a central role in inducing gene transcription during the immune response. Alternate transcriptional splice variants encoding different isoforms have been characterized.

Research Area: Cancer, Cardiovascular, Epigenetics and Nuclear Signaling, Metabolism, Immunology, Signal Transduction

Synonyms:
NFATC2, NFAT1, NFATP

Immunogen: A synthetic peptide of human NFATC2

Swissprot: Q13469
Gene ID: 4773

Calculated MW: 76 kDa/97 kDa/98 kDa/99 kDa/100 kDa
Observed MW: 130 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:1000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.