NFATC4 Polyclonal Antibody

Background:
The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction

Synonyms:
cytoplasmic 4, NF ATc4, NF-AT3, NF-ATc4, NFAC4, NFAT3, NFATc4, Nuclear factor of activated T cells cytoplasmic 4, Nuclear factor of activated T cells cytoplasmic calcineurin dependent 4, Nuclear factor of activated T-cells, T cell transcription factor NFAT3, T-cell transcription factor NFAT3

Immunogen: Recombinant Human Nuclear factor of activated T-cells protein

Swissprot: Q14934

Purification Method: Affinity purification

Buffer: PBS with 0.05% Proclin300 and 50% glycerol, pH7.4.

Concentration: 2 mg/mL
Dilution: IHC 1:100-1:400

Storage:
Store at -20°C. Avoid freeze / thaw cycles.