NFE2L2 polyclonal, anti-human, mouse, rat

Protein Family: Transcription Factors

Pathway and Disease: Folding, Sorting and Degradation, Transcription

Description:
Nuclear factor erythroid 2-related factor 2 (NFE2L2) is a transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. NFE2L2 is important for the coordinated up-regulation of genes in response to oxidative stress. NFE2L2 is involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

Alternate Names: NRF2, Nuclear factor-E2-related factor2, Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, Nuclear factor, erythroid derived 2, like 2, HEBP1, NFE2L2

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: Q16236

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human NFE2L2.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.

Product Citations:
[1] Padiya R et al. 2014. PLoS One. 9(5): e94228. PMID# 24796753.
[2] Bagul P et al. 2012. Pharmacol Res. 66(3): 260-8. PMID 22627169.