NFE4 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP21387c
Catalog Number: AC-AP21387c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51302
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB51302
Applications: WB
Datasheet
Request Information
Background:
Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.
Other Names:
Transcription factor NF-E4, NFE4
Target/Specificity:
This NFE4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 102-136 amino acids from the Central region of human NFE4.
Antigen Region:
102-136
Gene Name: NFE4
Primary Accession: Q86UQ8
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Functions as part of the SSP (stage selector protein) complex, a complex that contributes to the preferential expression of the gamma-gene in fetal erythroid cells by facilitating the interaction of the gamma-globin genes with enhancer elements contained in the locus control region (LCR). The complex binds to the stage selector element (SSE) in the proximal gamma-globin promoter. In contrast, isoform 2 acts as a repressor of gamma- globin gene expression by preventing NFE2 and RNA polymerase II recruitment to the promoter.
Other Names:
Transcription factor NF-E4, NFE4
Target/Specificity:
This NFE4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 102-136 amino acids from the Central region of human NFE4.
Antigen Region:
102-136
Gene Name: NFE4
Primary Accession: Q86UQ8
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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