NFkB p100/p52 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
NFKB2, also known as nuclear factor NF-kappa-B p100 subunit, is a protein that in humans is encoded by the NFKB2 gene. It is mapped to 10q24.32. This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFKB). NFKB is activated by a wide variety of stimuli such as cytokines, oxidant-free radicals, inhaled particles, ultraviolet irradiation, and bacterial or viral products. The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner.

Description:
Rabbit IgG polyclonal antibody for Nuclear factor NF-kappa-B p100 subunit (NFKB2) detection. Tested with WB, IHC-P in Human, Mouse, Rat.

Synonyms:
DNA binding factor KBF2 antibody, DNA-binding factor KBF2 antibody, H2TF1 antibody, Lymphocyte translocation chromosome 10 antibody, Lymphocyte translocation chromosome 10 protein antibody, Lyt 10 antibody, Lyt10 antibody, NF kB2 antibody, NFKB2 antibody, NFKB2_HUMAN antibody, Nuclear factor NF kappa B p100 subunit antibody, Nuclear factor NF kappa B p52 subunit antibody, Nuclear factor NF-kappa-B p52 subunit antibody, Nuclear factor of kappa light chain gene enhancer in B cells 2 antibody, Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 antibody, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 antibody, Oncogene Lyt 10 antibody, Oncogene Lyt-10 antibody, p105 antibody, p49/p100 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
E.coli-derived human NFkB p100/p52 recombinant protein (Position: M1-R340). Human NFkB p100/p52 shares 96% amino acid (aa) sequence identity with mouse NFkB p100/p52.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, mouse, rat

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.