NFkB-p100 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70527
Background:
This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.
Alternative Name:
p52, p105, H2TF1, LYT10, LYT-10, NF-kB2,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: NFkB-p100 polyclonal antibody detects endogenous levels of NFkB-p100 protein.
Immunogen:
A synthetic peptide of human NFKB2.
MW: ~ 97 kDa
Swis Prot.: Q00653
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.
Alternative Name:
p52, p105, H2TF1, LYT10, LYT-10, NF-kB2,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: NFkB-p100 polyclonal antibody detects endogenous levels of NFkB-p100 protein.
Immunogen:
A synthetic peptide of human NFKB2.
MW: ~ 97 kDa
Swis Prot.: Q00653
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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