NFκB-p100 Polyclonal Antibody

Background:
This gene encodes one of the subunits of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB transcription factor complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The NFkB complex can consist of different subunits that form both homo- or heterodimers which bind specific kappa-B elements in target genes. This gene encodes the p100 subunit that is processed into the active p52 subunit. This protein can function as both a transcriptional activator and repressor, depending on its dimer partner. Alternate splicing results in both coding and non-coding variants.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
CVID10, DNA binding factor KBF2, H2TF1, Lymphocyte translocation chromosome 10 protein, LYT 10, NF kB2, NFKB p52/p100 subunit, Nuclear factor Kappa B subunit 2, Nuclear factor of kappa light polypeptide gene enhancer in B cells 2 (p49/p100), Nuclear factor of kappa light polypeptide gene enhancer in B cells 2, Oncogene Lyt 10, p100, Transcription factor NFKB2

Immunogen: Synthetic peptide of human NFKB2

Swissprot: Q00653
Gene Accession: NP_001070962

Calculated MW: 97 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.5 mg/mL
Dilution: WB 1:1000-1:5000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-298/sc-848