NFKB p105/p50 Peptide
€100.00
In stock
SKU
350535
Protein Family: Transcription Factors
Pathway and Disease: Cancers, Cell Growth and Death, Endocrine System, Immune System, Infectious Diseases, Signal Transduction
Alternate Names: Nuclear factor NF-kappa-B p105/p50 subunit; DNA-binding factor KBF1; EBP-1; NFKB1
Accession No.: P19838, NP_003989
Description:
Nuclear factor NF-kappa-B p105/p50 subunit (NFKB1) is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RelA/p65, RelB, NFKB1/p105, NFKB1/p50, Rel and NFKB2/p52. Homo- and heterodimers bind with different affinities at kappa-B sites in the DNA of their target genes.
Format:
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 1774 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200173 is selected from a sequence within the C-term region of human NFKB p105/p50. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C74H116N24O23S2
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
Pathway and Disease: Cancers, Cell Growth and Death, Endocrine System, Immune System, Infectious Diseases, Signal Transduction
Alternate Names: Nuclear factor NF-kappa-B p105/p50 subunit; DNA-binding factor KBF1; EBP-1; NFKB1
Accession No.: P19838, NP_003989
Description:
Nuclear factor NF-kappa-B p105/p50 subunit (NFKB1) is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RelA/p65, RelB, NFKB1/p105, NFKB1/p50, Rel and NFKB2/p52. Homo- and heterodimers bind with different affinities at kappa-B sites in the DNA of their target genes.
Format:
Each vial contains 0.1 ml peptide in deionized water for a final concentration of 1 mg/ml. Use at 5.6 ug/ml for a 100X excess over antibody for maximum blocking effect.
MW: 1774 g/mol
Sequence:
The synthetic peptide used to raise the antibody Cat. No. 200173 is selected from a sequence within the C-term region of human NFKB p105/p50. For blocking experiments, a 10 to 100 fold molar excess to antibody is recommended.
Composition:
C74H116N24O23S2
Purity:
> 80% by HPLC
Solubility:
Distilled water for a solution up to 2 mg/ml, otherwise we recommend using acetonitrile.
Storage:
Store at -20°C. The product is hygroscopic and must be protected from light. Product is guaranteed one year from the date of shipment. Following reconstitution, store at -20°C.
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