NFkB-p65 (phospho-S536) polyclonal, anti-human, mouse, rat
€328.00
In stock
SKU
BS5088
Background:
p65 is a subunit of the nuclear factor kappa B. The transcription factor NFkB is widely recognized as a critical mediator of immune and inflammatory responses. In most cell types, NFkB is found in the cytoplasm where it is associated with an inhibitory prd in many tissues. A high proportion of spontaneous NIH/3T3 transformants overexpress c-Met and by transfection analysis the c-Met proto-oncogene has been shown to exhibittransforming activity.
Alternative Name:
p65, p65 NF kappaB, p65 NFkB, RELA, NFKB P65, Transcription Factor p65, Nuclear factor NF-kappa-B p65 subunit, NFkB-p65, NFKB3
Application Dilution: IHC: 1:50~1:200
Specificity: p-NFkB-p65 (S536) polyclonal antibody detects endogenous levels of NFkB-p65 protein only when phosphorylated at Ser536.
MW: ~ 60, 75 kDa
Swis Prot.: Q04206
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
p65 is a subunit of the nuclear factor kappa B. The transcription factor NFkB is widely recognized as a critical mediator of immune and inflammatory responses. In most cell types, NFkB is found in the cytoplasm where it is associated with an inhibitory prd in many tissues. A high proportion of spontaneous NIH/3T3 transformants overexpress c-Met and by transfection analysis the c-Met proto-oncogene has been shown to exhibittransforming activity.
Alternative Name:
p65, p65 NF kappaB, p65 NFkB, RELA, NFKB P65, Transcription Factor p65, Nuclear factor NF-kappa-B p65 subunit, NFkB-p65, NFKB3
Application Dilution: IHC: 1:50~1:200
Specificity: p-NFkB-p65 (S536) polyclonal antibody detects endogenous levels of NFkB-p65 protein only when phosphorylated at Ser536.
MW: ~ 60, 75 kDa
Swis Prot.: Q04206
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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