NFkB p65 polyclonal, anti-human, mouse, rat

Protein Family: Transcription Factors

Pathway and Disease: Cancers, Cell Growth and Death, Endocrine System, Immune System, Infectious Diseases, Signal Transduction, Transcription

Description:
NFKB p65 (Nuclear factor NF-kappa-B p65 subunit) is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RelA/p65, RelB, NFKB1/p105, NFKB1/p50, Rel and NFKB2/p52. Homo- and heterodimers bind with different affinities at kappa-B sites in the DNA of their target genes. The heterodimeric p65-p50 complex is the most abundant one.

Alternate Names: Transcription factor p65, Nuclear factor NF-kappa-B p65 subunit, RELA, NFKB3, NFkB p65

Application Notes: E: 1:1,000-1:10,000; WB: 1:200-1:1,000; IHC: 1:100-1:500

Accession No.: Q04206

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within human NFkB p65.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 2% BSA with 0.09% sodium azide. Antibody was purified by peptide-affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.