NFKB2 (clone 2F10A7), anti-human
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In stock
SKU
BT-MCA4601
Catalog Number: BT-MCA4601
Size(s): 50μL, 100μL
Isotype: Mouse IgG2b
Reactivity: human
Application(s): FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG2b
Reactivity: human
Application(s): FCM
Datasheet
Request Information
Background:
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Research Area: Cell Biology
Synonyms: p52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49/p100
Immunogen: Purified recombinant fragment of human NFKB2 (AA: 712-900) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]
Research Area: Cell Biology
Synonyms: p52, p100, H2TF1, LYT10, CVID10, LYT-10, NF-kB2, p49/p100
Immunogen: Purified recombinant fragment of human NFKB2 (AA: 712-900) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
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