NFKB2 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a subunit of the transcription factor complex nuclear factor-kappa-B (NFkB). The NFkB complex is expressed in numerous cell types and functions as a central activator of genes involved in inflammation and immune function. The protein encoded by this gene can function as both a transcriptional activator or repressor depending on its dimerization partner. The p100 full-length protein is co-translationally processed into a p52 active form. Chromosomal rearrangements and translocations of this locus have been observed in B cell lymphomas, some of which may result in the formation of fusion proteins. There is a pseudogene for this gene on chromosome 18. Alternative splicing results in multiple transcript variants.

Synonyms: CVID10, H2TF1, LYT-10, LYT10, NF-kB2, p100, p49/p100, p52

Cellular Location: Cytoplasm Nucleus

Immunogen:
A synthetic peptide of human NFKB2

Gene Symbol: NFKB2

Gene ID: 4791

Swiss prot: Q00653

Calculated MW: 97kDa

Recommended dilution:
WB 1:500-2000, IHC 1:50-200, IF 1:50-200,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.