NFKBIA middle region polyclonal, anti-human, mouse, rat, pig, sheep, horse, bovine, dog

Background:
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.

Other Names:
NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3, NFKBIA, IKBA, MAD3, NFKBI

Immunogen:
The immunogen for anti-NFKBIA antibody: synthetic peptide directed towards the middle region of human NFKBIA

Gene Name:
NFKBIA
Gene Name:
4792
NCBI Accession:
NP_065390
Primary Accession: P25963
Other Accession: NM_020529;NP_065390
Purification: Affinity Purified
Format: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.