NFKBIA monoclonal, anti-human
€0.00
In stock
SKU
AC-AM2205b
Catalog Number: AC-AM2205b
Size: 80 µl, 400 µl
Isotype: mouse IgG1,κ
Clone Name: 1121CT8.6.1
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: mouse IgG1,κ
Clone Name: 1121CT8.6.1
Applications: WB
Datasheet
Request Information
Background:
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Other Names:
NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3, NFKBIA, IKBA, MAD3, NFKBI
Target/Specificity:
Purified His-tagged NFKBIA protein was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: NFKBIA
Gene ID: 4792
Primary Accession: P25963
NCBI Accession: NP_065390.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.
Other Names:
NF-kappa-B inhibitor alpha, I-kappa-B-alpha, IkB-alpha, IkappaBalpha, Major histocompatibility complex enhancer-binding protein MAD3, NFKBIA, IKBA, MAD3, NFKBI
Target/Specificity:
Purified His-tagged NFKBIA protein was used to produced this monoclonal antibody.
Antigen Type: Recombinant Protein
Gene Name: NFKBIA
Gene ID: 4792
Primary Accession: P25963
NCBI Accession: NP_065390.1
Format: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
| Is Featured? | No |
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