NFKBIB Polyclonal Antibody

Background:
The protein encoded by this gene belongs to the NF-kappa-B inhibitor family, which inhibit NF-kappa-B by complexing with, and trapping it in the cytoplasm. Phosphorylation of serine residues on these proteins by kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B, which translocates to the nucleus to function as a transcription factor. Alternatively spliced transcript variants have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction

Synonyms:
NFKBIB, IKBB, TRIP9

Immunogen: Recombinant fusion protein of human NFKBIB (NP_002494.2).

Swissprot: Q15653
Gene ID: 4793

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "IHC 1:50-1:200 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.