NFKBID polyclonal, anti-human

Background:
May regulate the expression of IL-2, IL-6, and other cytokines through regulation on NF-kappa-B activity. Functions in the regulation of inflammatory responses. May also regulate TCR-induced negative selection of thymocytes.IκBNS, the nuclear IκB-like protein encoded by Nfkbid, is required for the development of marginal zone and peritoneal B-1 B cells and additionally required for extrafollicular antibody responses to T-independent and -dependent immunogens.IκBNS has been identified as a member of the IκB family of NF-κB inhibitors, which undergoes induction upon TCR signaling. IκBNS mediates both positive and negative gene regulation, depending on individual cell type and/or cytokine.

Synonyms: TA-NFKBH, IkappaBNS

Cellular Location: Cytoplasm Nucleus

Immunogen:
Recombinant protein of human NFKBID

Gene Symbol: NFKBID

Gene ID: 84807

Swiss prot: Q8NI38

Calculated MW: 33kDa

Recommended dilution:
WB 1:2000-5000, IHC 1:10-100,

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.