NFKBIZ polyclonal, anti-human, mouse, rat

Background:
This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms: IKBZ, INAP, MAIL

Cellular Location: Nucleus

Immunogen:
Recombinant protein of human NFKBIZ

Gene Symbol: NFKBIZ

Gene ID: 64332

Swiss prot: Q9BYH8

Calculated MW: 78kDa

Recommended dilution:
WB 1:500-2000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.