NFKBIZ Polyclonal Antibody

Background:
This gene is a member of the ankyrin-repeat family and is induced by lipopolysaccharide (LPS). The C-terminal portion of the encoded product which contains the ankyrin repeats, shares high sequence similarity with the I kappa B family of proteins. The latter are known to play a role in inflammatory responses to LPS by their interaction with NF-B proteins through ankyrin-repeat domains. Studies in mouse indicate that this gene product is one of the nuclear I kappa B proteins and an activator of IL-6 production. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Immunology

Synonyms:
NFKBIZ, IKBZ, INAP, MAIL

Immunogen: Recombinant fusion protein of human NFKBIZ (NP_113607.1).

Swissprot: Q9BYH8
Gene ID: 64332

Calculated MW: 64 kDa/68 kDa/78 kDa
Observed MW: 68-90 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IF 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.