NFS1 Polyclonal Antibody

Background:
Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described.

Research Area: Metabolism, Signal transduction

Synonyms:
Cysteine desulfurase, Cysteine desulfurase, mitochondrial , HUSSY 08 , IscS, mitochondrial, NFS1, NFS1 nitrogen fixation 1, NFS1 nitrogen fixation 1 homolog (S. cerevisiae), NFS1, NIFS, nitrogen fixation 1 (S. cerevisiae, homolog), nitrogen fixation gene 1, nitrogen-fixing bacteria S, homolog of, nitrogen-fixing bacteria S-like protein, OTTHUMP00000030799

Immunogen: Fusion protein of human NFS1

Swissprot: Q9Y697
Gene Accession: BC018471

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.78 mg/mL
Dilution: IHC 1:50-1:200, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.