NFU1 Polyclonal Antibody

Background:
This gene encodes a protein that is localized to mitochondria and plays a critical role in iron-sulfur cluster biogenesis. The encoded protein assembles and transfers 4Fe-4S clusters to target apoproteins including succinate dehydrogenase and lipoic acid synthase. Mutations in this gene are a cause of multiple mitochondrial dysfunctions syndrome-1, and pseudogenes of this gene are located on the short arms of chromosomes 1 and 3. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Synonyms:
NFU1, CGI-33, HIRIP, HIRIP5, MMDS1, NIFUC, Nfu, NifU

Immunogen: Recombinant fusion protein of human NFU1 (NP_001002755.1).

Swissprot: Q9UMS0
Gene ID: 27247

Calculated MW: 12 kDa/25 kDa/28 kDa
Observed MW: 25-28 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.