NFYB Polyclonal Antibody

Background:
The protein encoded by this gene is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.

Research Area: Epigenetics and Nuclear Signaling, Signal Transduction

Synonyms:
NFYB, CBF-A, CBF-B, HAP3, NF-YB

Immunogen: Recombinant fusion protein of human NFYB (NP_006157.1).

Swissprot: P25208
Gene ID: 4801

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: IF 1:50-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.