NGAL (clone 8), anti-rat

NGAL (clone 8), anti-rat

€1,171.00
In stock
SKU
250247
Catalog Nr.: 250247
Size: 0.2 mg
Isotype: Mouse IgG1
Applications: E, IHC
Datasheet
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Protein Family: Transporters

Pathway and Disease: Membrane Transport

Description:
Rat NGAL, so called because it is the ortholog of human neutrophil gelatinase-associated lipocalin (NGAL), is also called lipocalin 2, 25-kDa alpha 2-microglobulin-related protein or neu-related lipocalin. It is expressed by neutrophils and various epithelial cells, including cells of the renal proximal tubules. It is involved in physiological processes such as the binding of siderophore iron and tissue growth and regeneration. It is upregulated in a variety of pathological situations including infection, inflammation, ischemia-reperfusion and in certain adenocarcinomas. This antibody binds rat NGAL and shows no cross-reaction with human, pig, dog and mouse NGAL.

Alternate Names: NGAL, p25, 25kDa alpha-2-microglobulin-related subunit of MMP-9, neutrophil gelatinase-associated lipocalin

Application Notes: Product Cat. No. 250247 binds free rat NGAL in solution. The ELISA dilution guideline applies to rat NGAL coated directly at 1.0 µg/mL. Product Cat. No. 250247 (as capture antibody) forms a sandwich ELISA pair with Product Cat. No. 250248 (as biotinylated detection antibody) for measuring rat NGAL, giving detection limit of 0.012 ng/mL in an unoptimized buffer assay. E: 1:125; IHC: 1:100-1:200

Accession No.: P80188

Antigen: Recombinant rat NGAL precursor with C-terminal His-tag coupled to carrier.

Format: Each vial contains 0.2 mg IgG in 0.2 ml (1 mg/ml) of PBS pH7.4 with 0.09% sodium azide. Antibody was purified by Protein-A/G affinity chromatography.

Storage:
Store at 4°C. Product is guaranteed 6 months from the date of shipment.
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