NGF-beta polyclonal, anti-human, mouse, rat

Protein Family: Chaperones and Folding Catalysts, Cytokines

Pathway and Disease: Signal Transduction, Cell Growth and Death, Nervous and Sensory Systems

Description:
Nerve growth factor (NGF-beta) is important for the development and maintenance of the sympathetic and sensory nervous systems. NGF-beta stimulates division and differentiation of sympathetic and embryonic sensory neurons. Defects in NGF-beta are the cause of hereditary sensory and autonomic neuropathy type 5 (HSAN5). The hereditary sensory and autonomic neuropathies are a genetically and clinically heterogeneous group of disorders characterized by degeneration of dorsal root and autonomic ganglion cells, and by sensory and/or autonomic abnormalities.

Alternate Names: Beta-nerve growth factor, beta-NGF, NGF, NGFB, NGF-beta

Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500

Accession No.: P01138

Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human NGF-beta.

Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 5% BSA with 0.09% sodium azide. Antibody was purified by Protein-G affinity chromatography.

Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.