NGFR polyclonal (C-term), anti-human, rat
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In stock
SKU
AC-AP21641b
Catalog Number: AC-AP21641b
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB53291
Applications: WB
Datasheet
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Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB53291
Applications: WB
Datasheet
Request Information
Background:
Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
Other Names:
Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, p75 ICD, CD271, NGFR, TNFRSF16
Target/Specificity:
This NGFR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 276-310 amino acids from the C-terminal region of human NGFR.
Gene Name: NGFR
Gene ID: 4804
Primary Accession: P08138
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Plays a role in the regulation of the translocation of GLUT4 to the cell surface in adipocytes and skeletal muscle cells in response to insulin, probably by regulating RAB31 activity, and thereby contributes to the regulation of insulin-dependent glucose uptake (By similarity). Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Necessary for the circadian oscillation of the clock genes ARNTL/BMAL1, PER1, PER2 and NR1D1 in the suprachiasmatic nucleus (SCN) of the brain and in liver and of the genes involved in glucose and lipid metabolism in the liver.
Other Names:
Tumor necrosis factor receptor superfamily member 16, Gp80-LNGFR, Low affinity neurotrophin receptor p75NTR, Low-affinity nerve growth factor receptor, NGF receptor, p75 ICD, CD271, NGFR, TNFRSF16
Target/Specificity:
This NGFR antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 276-310 amino acids from the C-terminal region of human NGFR.
Gene Name: NGFR
Gene ID: 4804
Primary Accession: P08138
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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