NHE-7 rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene encodes a sodium and potassium/ proton antiporter that is a member of the solute carrier family 9 protein family. The encoded protein is primarily localized to the trans-Golgi network and is involved in maintaining pH homeostasis in organelles along the secretory and endocytic pathways. This protein may enhance cell growth of certain breast tumors. This gene is part of a gene cluster on chromosome Xp11.23. A pseudogene of this gene is found on chromosome 12. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012],function:Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to Golgi volume and cation homeostasis.,miscellaneous:Is not inhibited by amiloride but by benzamil and quinine.,similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.,subunit:Interacts with SCAMP1, SCAMP2 and SCAMP5; may participate in its shuttling from trans-Golgi network to recycling endosomes.,tissue specificity:Ubiquitously expressed.,

Synonyms: SLC9A7, NHE7, Sodium/hydrogen exchanger 7, Na(+)/H(+) exchanger 7, NHE-7, Solute carrier family 9 member 7

Gene Name: SLC9A7

Gene ID: 84679

SwissProt ID: Q96T83

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.