NHE-8 rabbit polyclonal, anti-human, mouse, rat

Backgroud: Sodium-hydrogen exchangers (NHEs), such as SLC9A8, are integral transmembrane proteins that exchange extracellular Na+ for intracellular H+. NHEs have multiple functions, including intracellular pH homeostasis, cell volume regulation, and electroneutral NaCl absorption in epithelia (Xu et al., 2008 [PubMed 18209477]).[supplied by OMIM, Apr 2009],function:Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.,similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.,tissue specificity:Ubiquitous. Strongly expressed in skeletal muscle and kidney.,

Synonyms: SLC9A8, KIAA0939, NHE8, Sodium/hydrogen exchanger 8, Na(+)/H(+) exchanger 8, NHE-8, Solute carrier family 9 member 8

Gene Name: SLC9A8

Gene ID: 23315

SwissProt ID: Q9Y2E8

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.