GPR40 polyclonal, anti-human, primate
€470.00
In stock
SKU
AC-AP70202
Background:
G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose- stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.
Other Names:
FFAR1; GPR40; Free fatty acid receptor 1; G-protein coupled receptor 40
Antigen Type: synthetic peptide
Antigen Type: FFAR1
Gene ID: 2864
Primary Accession: O14842
G-protein coupled receptor for medium and long chain saturated and unsaturated fatty acids that plays an important role in glucose homeostasis. Fatty acid binding increases glucose- stimulated insulin secretion, and may also enhance the secretion of glucagon-like peptide 1 (GLP-1). May also play a role in bone homeostasis; receptor signaling activates pathways that inhibit osteoclast differentiation (By similarity). Ligand binding leads to a conformation change that triggers signaling via G-proteins that activate phospholipase C, leading to an increase of the intracellular calcium concentration. Seems to act through a G(q) and G(i)-mediated pathway.
Other Names:
FFAR1; GPR40; Free fatty acid receptor 1; G-protein coupled receptor 40
Antigen Type: synthetic peptide
Antigen Type: FFAR1
Gene ID: 2864
Primary Accession: O14842
| Is Featured? | No |
|---|
Write Your Own Review