NHEJ1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS70661
Background:
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
Alternative Name:
XLF, Protein cernunnos, XRCC4-like factor
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: NHEJ1 polyclonal antibody detects endogenous levels of NHEJ1 protein.
Immunogen:
Recombinant protein of human NHEJ1.
MW: ~ 33 kDa
Swis Prot.: Q9H9Q4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders.
Alternative Name:
XLF, Protein cernunnos, XRCC4-like factor
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: NHEJ1 polyclonal antibody detects endogenous levels of NHEJ1 protein.
Immunogen:
Recombinant protein of human NHEJ1.
MW: ~ 33 kDa
Swis Prot.: Q9H9Q4
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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