Nicotinic Acetylcholine Receptor alpha 1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
CHRNA, also termed ACHRA, is mapped on 2q24-q32.This gene encodes the alpha subunit of the muscle acetylcholine receptor, which is the main target of pathogenic autoantibodies in autoimmune myasthenia gravis. The protein-coding sequence of the human alpha subu gene is divided into 9 exons that correspond to different structural and functional domains of the precursor molecule.

Description:
Rabbit IgG polyclonal antibody for Acetylcholine receptor subunit alpha (CHRNA1) detection. Tested with WB in Human, Mouse, Rat.

Synonyms:
Acetylcholine receptor subunit alpha antibody, ACHA_HUMAN antibody, ACHRA antibody, ACHRD antibody, CHNRA antibody, Cholinergic receptor nicotinic alpha polypeptide 1 antibody, Cholinergic receptor, nicotinic, alpha polypeptide 1(muscle) antibody, CHRNA antibody, Chrna1 antibody, CMS2A antibody, FCCMS antibody, Nicotinic cholinergic receptor alpha 1 antibody, SCCMS antibody, Schizophrenia neurophysiologic defect candidate antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human Nicotinic Acetylcholine Receptor alpha 1(22-36aa EHETRLVAKLFKDYS), identical to the related rat sequence, different from the related mouse sequence by one amino acid.A synthetic peptide corresponding to a sequence at the N-terminus of human Nicotinic Acetylcholine Receptor alpha 1(22-36aa EHETRLVAKLFKDYS), identical to the related rat sequence, different from the related mouse sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.