NIFUN antibody (clone 3B8-1C4), anti-human

Background:
Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins. They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins. This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein. Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.

Other Names:
Iron-sulfur cluster assembly enzyme ISCU, mitochondrial, NifU-like N-terminal domain-containing protein, NifU-like protein, ISCU, NIFUN

Antigen Type:
Recombinant Protein

Gene Name: ISCU (HGNC:29882)
Gene ID: 23479
NCBI Accession: NP_055116.1;NP_998760.1
Primary Accession: Q9H1K1
Other Accession: BC011906
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .