NIS polyclonal, anti-human, mouse, rat, pig
€422.00
In stock
SKU
250552
Catalog Nr.: 250552
Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
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Size: 0.1 mg
Isotype: Rabbit Ig
Applications: E, WB, IHC
Datasheet
Request Information
Protein Family: Transporters
Pathway and Disease: Endocrine System
Description:
The natrium-iodide symporter (NIS) is a key plasma membrane protein that mediates active iodine uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated iodine uptake is the first step in the biosynthesis of iodine-containing thyroid hormones.
Alternate Names: Sodium iodide cotransporter, Na(+)/I(-) cotransporter, Sodium-iodide symporter, Solute carrier family 5 member 5, SLC5A5, NIS
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: Q92911
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of mouse NIS.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Tran L et al. 2013. Exp Biol Med. 238(6):623-630. PMID# 23918874.
[2] Basalaeva, NL et al. 2013. Biological Trace Element Research. 154(2):244-254. PMID# 23771684.
Pathway and Disease: Endocrine System
Description:
The natrium-iodide symporter (NIS) is a key plasma membrane protein that mediates active iodine uptake in thyroid, lactating breast, and other tissues with an electrogenic stoichiometry of 2 Na+ per I-. In thyroid, NIS-mediated iodine uptake is the first step in the biosynthesis of iodine-containing thyroid hormones.
Alternate Names: Sodium iodide cotransporter, Na(+)/I(-) cotransporter, Sodium-iodide symporter, Solute carrier family 5 member 5, SLC5A5, NIS
Application Notes: E: 1:500-1:1,000; WB: 1:100-1:500; IHC: 1:100-1:500
Accession No.: Q92911
Antigen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of mouse NIS.
Format: Each vial contains 0.1 mg IgG in 0.1 ml (1 mg/ml) of PBS pH7.4, 25% glycerol, 1 mg/ml BSA with 0.09% sodium azide. Antibody was purified by Protein-A affinity chromatography.
Storage:
Store at -20°C. Minimize freeze-thaw cycles. Product is guaranteed one year from the date of shipment.
Product Citations:
[1] Tran L et al. 2013. Exp Biol Med. 238(6):623-630. PMID# 23918874.
[2] Basalaeva, NL et al. 2013. Biological Trace Element Research. 154(2):244-254. PMID# 23771684.
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