NK-1R rabbit polyclonal, anti-human, mouse, rat

Backgroud: This gene belongs to a gene family of tachykinin receptors. These tachykinin receptors are characterized by interactions with G proteins and contain seven hydrophobic transmembrane regions. This gene encodes the receptor for the tachykinin substance P, also referred to as neurokinin 1. The encoded protein is also involved in the mediation of phosphatidylinositol metabolism of substance P. [provided by RefSeq, Sep 2008],function:This is a receptor for the tachykinin neuropeptide substance P. It is probably associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance P > substance K > neuromedin-K.,online information:Tachykinin entry,similarity:Belongs to the G-protein coupled receptor 1 family.,

Synonyms: TACR1, NK1R, TAC1R, Substance-P receptor, SPR, NK-1 receptor, NK-1R, Tachykinin receptor 1

Gene Name: TACR1

Gene ID: 6869

SwissProt ID: P25103

Purification: Affinity purification

Storage: Store at 4°C short term. Aliquot and store at -20°C for 12 months. Avoid freeze/thaw cycles.