NKCC1 polyclonal, anti-human, mouse, rat

Quantity: 100 µg

Background:
Solute carrier family 12(sodium/potassium/chloride transporters), member 2, also known as NKCC1, is widely distributed throughout the body, especially in organs that secrete fluids, called exocrine glands. By fluorescence in situ hybridization, this gene is mapped to chromosome 5q23.3. The protein encoded by this gene mediates sodium and chloride transport and reabsorption. The encoded protein is a membrane protein and is important in maintaining proper ionic balance and cell volume. This protein is phosphorylated in response to DNA damage. Three transcript variants encoding two different isoforms have been found for this gene.

Description:
Rabbit IgG polyclonal antibody for Solute carrier family 12 member 2 (SLC12A2) detection. Tested with WB, IHC-P, IHC-F in Human, Mouse, Rat.

Synonyms:
Basolateral Na-K-Cl symporter antibody, BSC antibody, BSC2 antibody, Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 1 antibody, mBSC2 antibody, MGC104233 antibody, NKCC1 antibody, S12A2_HUMAN antibody, SLC12A2 antibody, sodium-potassium-chloride cotransporter 1 antibody, solute carrier family 12(sodium/potassium/chloride transporters) member 2 antibody, Solute carrier family 12 member 2 antibody, sy-ns antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the N-terminus of human NKCC1(223-241aa RIDHYRHTAAQLGEKLLRP), identical to the related mouse and rat sequences.A synthetic peptide corresponding to a sequence at the N-terminus of human NKCC1(223-241aa RIDHYRHTAAQLGEKLLRP), identical to the related mouse and rat sequences.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human, rat .
Predicted to work with: mouse.

Applications: WB, IHC-P, IHC-F

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.