NKG2D Antibody (N-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13295a
Background:
Natural killer (NK) cells are lymphocytes that can mediatelysis of certain tumor cells and virus-infected cells withoutprevious activation. They can also regulate specific humoral andcell-mediated immunity. NK cells preferentially express severalcalcium-dependent (C-type) lectins, which have been implicated inthe regulation of NK cell function. This gene encodes a member ofthe NKG2 family, and the encoded transmembrane protein ischaracterized by a type II membrane orientation (extracellular Cterminus) and the presence of a C-type lectin domain. The NKG2 genefamily is located within the NK complex, a region that containsseveral C-type lectin genes preferentially expressed in NK cells.
Other Names:
NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, KLRK1, D12S2489E, NKG2D
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13295a was selected from the N-term region of NKG2D. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: KLRK1
Gene ID: 100528032;22914
Primary Accession: P26718
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Natural killer (NK) cells are lymphocytes that can mediatelysis of certain tumor cells and virus-infected cells withoutprevious activation. They can also regulate specific humoral andcell-mediated immunity. NK cells preferentially express severalcalcium-dependent (C-type) lectins, which have been implicated inthe regulation of NK cell function. This gene encodes a member ofthe NKG2 family, and the encoded transmembrane protein ischaracterized by a type II membrane orientation (extracellular Cterminus) and the presence of a C-type lectin domain. The NKG2 genefamily is located within the NK complex, a region that containsseveral C-type lectin genes preferentially expressed in NK cells.
Other Names:
NKG2-D type II integral membrane protein, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2-D-activating NK receptor, CD314, KLRK1, D12S2489E, NKG2D
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13295a was selected from the N-term region of NKG2D. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: KLRK1
Gene ID: 100528032;22914
Primary Accession: P26718
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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