NKIRAS1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP17459c
Catalog Number: AC-AP17459c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37274
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37274
Applications: WB
Datasheet
Request Information
Background:
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB.
Other Names:
NF-kappa-B inhibitor-interacting Ras-like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B-Ras protein 1, KappaB-Ras1, NKIRAS1, KBRAS1
Target/Specificity:
This NKIRAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the Central region of human NKIRAS1.
Antigen Region:
48-76
Antigen Type: Synthetic Peptide
Gene Name: NKIRAS1
Gene ID: 28512
Primary Accession: Q9NYS0
NCBI Accession: NP_065078.1
Other Accession: Q9BH04; NP_065078.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and mediating cytoplasmic retention of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB.
Other Names:
NF-kappa-B inhibitor-interacting Ras-like protein 1, I-kappa-B-interacting Ras-like protein 1, Kappa B-Ras protein 1, KappaB-Ras1, NKIRAS1, KBRAS1
Target/Specificity:
This NKIRAS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 48-76 amino acids from the Central region of human NKIRAS1.
Antigen Region:
48-76
Antigen Type: Synthetic Peptide
Gene Name: NKIRAS1
Gene ID: 28512
Primary Accession: Q9NYS0
NCBI Accession: NP_065078.1
Other Accession: Q9BH04; NP_065078.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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