NKIRAS2 polyclonal (Center), anti-human

NKIRAS2 polyclonal (Center), anti-human

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In stock
SKU
AC-AP16523c
Catalog Number: AC-AP16523c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB36021
Applications: WB
Datasheet

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Background:
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB (By similarity).

Other Names:
NF-kappa-B inhibitor-interacting Ras-like protein 2, I-kappa-B-interacting Ras-like protein 2, Kappa B-Ras protein 2, KappaB-Ras2, NKIRAS2, KBRAS2

Target/Specificity:
This NKIRAS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 amino acids from the Central region of human NKIRAS2.

Antigen Region:
36-64

Antigen Type: Synthetic Peptide

Gene Name: NKIRAS2
Gene ID: 28511
Primary Accession: Q9NYR9
NCBI Accession: NP_001001349.1;NP_001138399.1;NP_001138400.1;NP_001138401.1;NP_060065.2
Other Accession: Q32NS2; Q9CR56; Q5ZJW6; NP_060065.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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