NKX2-1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP17825c
Catalog Number: AC-AP17825c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37578
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB37578
Applications: WB
Datasheet
Request Information
Background:
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Homeobox protein Nkx-21, Homeobox protein NK-2 homolog A, Thyroid nuclear factor 1, Thyroid transcription factor 1, TTF-1, Thyroid-specific enhancer-binding protein, T/EBP, NKX2-1, NKX2A, TITF1, TTF1
Target/Specificity:
This NKX2-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-226 amino acids from the Central region of human NKX2-1.
Antigen Region:
2-1
Antigen Type: Synthetic Peptide
Gene Name: NKX2-1 (HGNC:11825)
Gene ID: 7080
Primary Accession: P43699
NCBI Accession: NP_001073136.1;NP_003308.1
Other Accession: Q9EQM3; Q9H2Z4; P23441; P50220; NP_003308.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Homeobox protein Nkx-21, Homeobox protein NK-2 homolog A, Thyroid nuclear factor 1, Thyroid transcription factor 1, TTF-1, Thyroid-specific enhancer-binding protein, T/EBP, NKX2-1, NKX2A, TITF1, TTF1
Target/Specificity:
This NKX2-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 197-226 amino acids from the Central region of human NKX2-1.
Antigen Region:
2-1
Antigen Type: Synthetic Peptide
Gene Name: NKX2-1 (HGNC:11825)
Gene ID: 7080
Primary Accession: P43699
NCBI Accession: NP_001073136.1;NP_003308.1
Other Accession: Q9EQM3; Q9H2Z4; P23441; P50220; NP_003308.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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