NKX2.2 (Neuroendocrine & Ewing Sarcoma Marker) (clone SPM564 ), anti-human, mouse, chicken
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In stock
SKU
AC-AH10640
Catalog Number: AC-AH10640
Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM564
Applications: IHC-P, IF, FC
Datasheet
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Size: 20 µg, 100 µg
Isotype: Mouse
Clone Name: SPM564
Applications: IHC-P, IF, FC
Datasheet
Request Information
Background:
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Other Names:
Homeobox protein Nkx-2.2, Homeobox protein NK-2 homolog B, NKX2-2, NKX2.2, NKX2B
Gene Name: NKX2-2
Gene ID: 4821
Primary Accession: O95096
Other Accession: 4821, 516922
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
Other Names:
Homeobox protein Nkx-2.2, Homeobox protein NK-2 homolog B, NKX2-2, NKX2.2, NKX2B
Gene Name: NKX2-2
Gene ID: 4821
Primary Accession: O95096
Other Accession: 4821, 516922
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