NKX3-1 polyclonal (Center), anti-human
€0.00
In stock
SKU
AC-AP8996C
Catalog Number: AC-AP8996C
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23610
Applications: FC, IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB23610
Applications: FC, IHC-P, WB
Datasheet
Request Information
Background:
NKX3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. It Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Other Names:
Homeobox protein Nkx-31, Homeobox protein NK-3 homolog A, NKX3-1, NKX31, NKX3A
Target/Specificity:
This NKX3-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human NKX3-1.
Antigen Region:
3-1
Antigen Type: Synthetic Peptide
Gene Name: NKX3-1 (HGNC:7838)
Gene ID: 4824
Primary Accession: Q99801
NCBI Accession: NP_001243268.1;NP_006158.2
Other Accession: P97436
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
NKX3-1 is a transcription factor, which binds preferentially the consensus sequence 5'-TAAGT[AG]-3' and can behave as a transcriptional repressor. It play an important role in normal prostate development, regulating proliferation of glandular epithelium and in the formation of ducts in prostate. It Acts as a tumor suppressor controlling prostate carcinogenesis, as shown by the ability to inhibit proliferation and invasion activities of PC-3 prostate cancer cells.
Other Names:
Homeobox protein Nkx-31, Homeobox protein NK-3 homolog A, NKX3-1, NKX31, NKX3A
Target/Specificity:
This NKX3-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-145 amino acids from the Central region of human NKX3-1.
Antigen Region:
3-1
Antigen Type: Synthetic Peptide
Gene Name: NKX3-1 (HGNC:7838)
Gene ID: 4824
Primary Accession: Q99801
NCBI Accession: NP_001243268.1;NP_006158.2
Other Accession: P97436
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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