NLRP10 Antibody (C-term) Blocking peptide
€363.00
In stock
SKU
AC-BP13494b
Background:
Members of the NALP protein family typically contain aNACHT domain, a NACHT-associated domain (NAD), a C-terminalleucine-rich repeat (LRR) region, and an N-terminal pyrin domain(PYD). The protein encoded by this gene belongs to the NALP proteinfamily despite lacking the LRR region. This protein likely plays aregulatory role in the innate immune system. The protein belongs tothe signal-induced multiprotein complex, the inflammasome, thatactivates the pro-inflammatory caspases, caspase-1 and caspase-5.Other experiments indicate that this gene acts as a multifunctionalnegative regulator of inflammation and apoptosis. [provided byRefSeq].
Other Names:
NACHT, LRR and PYD domains-containing protein 10, Nucleotide-binding oligomerization domain protein 8, NLRP10, NALP10, NOD8, PYNOD
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13494b was selected from the C-term region of NLRP10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NLRP10
Gene ID: 338322
Primary Accession: Q86W26
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Members of the NALP protein family typically contain aNACHT domain, a NACHT-associated domain (NAD), a C-terminalleucine-rich repeat (LRR) region, and an N-terminal pyrin domain(PYD). The protein encoded by this gene belongs to the NALP proteinfamily despite lacking the LRR region. This protein likely plays aregulatory role in the innate immune system. The protein belongs tothe signal-induced multiprotein complex, the inflammasome, thatactivates the pro-inflammatory caspases, caspase-1 and caspase-5.Other experiments indicate that this gene acts as a multifunctionalnegative regulator of inflammation and apoptosis. [provided byRefSeq].
Other Names:
NACHT, LRR and PYD domains-containing protein 10, Nucleotide-binding oligomerization domain protein 8, NLRP10, NALP10, NOD8, PYNOD
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP13494b was selected from the C-term region of NLRP10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: NLRP10
Gene ID: 338322
Primary Accession: Q86W26
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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