NLRP10 polyclonal (C-term), anti-human
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In stock
SKU
AC-AP13494b
Catalog Number: AC-AP13494b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33404
Applications: WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB33404
Applications: WB
Datasheet
Request Information
Background:
Members of the NALP protein family typically contain aNACHT domain, a NACHT-associated domain (NAD), a C-terminalleucine-rich repeat (LRR) region, and an N-terminal pyrin domain(PYD). The protein encoded by this gene belongs to the NALP proteinfamily despite lacking the LRR region. This protein likely plays aregulatory role in the innate immune system. The protein belongs tothe signal-induced multiprotein complex, the inflammasome, thatactivates the pro-inflammatory caspases, caspase-1 and caspase-5.Other experiments indicate that this gene acts as a multifunctionalnegative regulator of inflammation and apoptosis. [provided byRefSeq].
Other Names:
NACHT, LRR and PYD domains-containing protein 10, Nucleotide-binding oligomerization domain protein 8, NLRP10, NALP10, NOD8, PYNOD
Target/Specificity:
This NLRP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 466-494 amino acids from the C-terminal region of human NLRP10.
Antigen Region:
466-494
Antigen Type: Synthetic Peptide
Gene Name: NLRP10
Gene ID: 338322
Primary Accession: Q86W26
NCBI Accession: NP_789791.1
Other Accession: NP_789791.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Members of the NALP protein family typically contain aNACHT domain, a NACHT-associated domain (NAD), a C-terminalleucine-rich repeat (LRR) region, and an N-terminal pyrin domain(PYD). The protein encoded by this gene belongs to the NALP proteinfamily despite lacking the LRR region. This protein likely plays aregulatory role in the innate immune system. The protein belongs tothe signal-induced multiprotein complex, the inflammasome, thatactivates the pro-inflammatory caspases, caspase-1 and caspase-5.Other experiments indicate that this gene acts as a multifunctionalnegative regulator of inflammation and apoptosis. [provided byRefSeq].
Other Names:
NACHT, LRR and PYD domains-containing protein 10, Nucleotide-binding oligomerization domain protein 8, NLRP10, NALP10, NOD8, PYNOD
Target/Specificity:
This NLRP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 466-494 amino acids from the C-terminal region of human NLRP10.
Antigen Region:
466-494
Antigen Type: Synthetic Peptide
Gene Name: NLRP10
Gene ID: 338322
Primary Accession: Q86W26
NCBI Accession: NP_789791.1
Other Accession: NP_789791.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
| Is Featured? | No |
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