NLRP12/NALP12 (AL236) polyclonal, anti-human

Quantity: 100 µl

Description:
NALP12/NLRP12 mediates activation of caspase-1 via Asc and promotes activation of NF-kappa-B via IKK. It is involved in the building of an inflammasome complex. Defects in NALP12/NLRP12 are the cause of familial cold autoinflammatory syndrome type 2 (FCAS2).

Synonyms:
NLRP12, NACHT-, LRR- and PYD-containing Protein 12, PYRIN-containing APAF1-like Protein 7, Monarch-1, Regulated by Nitric Oxide, RNO

Isotype: Rabbit Polyclonal

Immunogen:
Synthetic peptide corresponding to a aa sequence near the N-terminus of human NLRP12/NALP12.

Form: Purified, in PBS containing 10% glycerol and 0.02% sodium azide.

Specificity:
Recognizes human NLRP12/NALP12.

Reactivity: human

Applications: Immunoprecipitation, Western Blot

Working DIlution: Optimal conditions must be determined individually for each application.

Storage: 2-8C immediate use, or -20C (aliquoted)